The Author, in the present research and in the population-based study of 40 eyes affected by various types of glaucoma, examined the correlation with possible iatrogenic side effects as well as the forensic aspects related to a possible progression of glaucoma, which does represent a crucial issue in social medicine as a result of the incidence of visual impairment in adulthood, wherever more specific drugs but with potentially adverse health effects cannot be used during pregnancy due to the magnitude and the variety of their pharmacological side effects. In fact, even in the case of a topical therapy with a very low anti-glaucomatous dosage, such as timolol 0.1% gel, a significant amount of its volume up to 80% results in systemic absorption, with all the associated iatrogenic effects, particularly dangerous during the first weeks of pregnancy. Furthermore, it is also important to consider the particular fetal physiology, which may determine a greater persistence in the circulation o
MEDICO-LEGAL ASPECTS OF THE USE OF GLAUCOMA MEDICATIONS IN PREGNANCY / Salducci, Mauro; Pacella, Fernanda; Pacella, Elena. - In: PREVENTION & RESEARCH. - ISSN 2240-2594. - STAMPA. - 4:3(2014), pp. 343-348.
MEDICO-LEGAL ASPECTS OF THE USE OF GLAUCOMA MEDICATIONS IN PREGNANCY
SALDUCCI, Mauro;PACELLA, FERNANDA;PACELLA, Elena
2014
Abstract
The Author, in the present research and in the population-based study of 40 eyes affected by various types of glaucoma, examined the correlation with possible iatrogenic side effects as well as the forensic aspects related to a possible progression of glaucoma, which does represent a crucial issue in social medicine as a result of the incidence of visual impairment in adulthood, wherever more specific drugs but with potentially adverse health effects cannot be used during pregnancy due to the magnitude and the variety of their pharmacological side effects. In fact, even in the case of a topical therapy with a very low anti-glaucomatous dosage, such as timolol 0.1% gel, a significant amount of its volume up to 80% results in systemic absorption, with all the associated iatrogenic effects, particularly dangerous during the first weeks of pregnancy. Furthermore, it is also important to consider the particular fetal physiology, which may determine a greater persistence in the circulation oI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.