We describe three children with gelastic seizures without hypothalamic hamartoma whose seizures were characterized by typical laughing attacks associated or not with other seizure types. Ictal/interictal EEG and magnetic resonance imaging were performed. All three subjects showed a good response to carbamazepine therapy with complete seizure control in addition to a benign clinical and cognitive outcome. These three cases confirm that gelastic epilepsy without hypothalamic hamartoma, both in cryptogenic or symptomatic patients (one child showed a dysplastic right parietotemporal lesion), usually has a more benign natural history, and carbamazepine seems to be the most efficacious therapy to obtain both immediate and long-term seizure control. These findings need to be confirmed in a larger sample of children affected by gelastic epilepsy without hypothalamic hamartoma.
Gelastic epilepsy without hypothalamic hamartoma. Three additional cases / Salvatore, Savasta; Mauro, Budetta; Maria Valentina, Sparta; Maria Luisa, Carpentieri; Trasimeni, Guido; Niki, Zavras; Villa, MARIA PIA; Parisi, Pasquale. - In: EPILEPSY & BEHAVIOR. - ISSN 1525-5050. - STAMPA. - 37:Aug.(2014), pp. 87-90. [10.1016/j.yebeh.2014.06.012]
Titolo: | Gelastic epilepsy without hypothalamic hamartoma. Three additional cases | |
Autori: | ||
Data di pubblicazione: | 2014 | |
Rivista: | ||
Citazione: | Gelastic epilepsy without hypothalamic hamartoma. Three additional cases / Salvatore, Savasta; Mauro, Budetta; Maria Valentina, Sparta; Maria Luisa, Carpentieri; Trasimeni, Guido; Niki, Zavras; Villa, MARIA PIA; Parisi, Pasquale. - In: EPILEPSY & BEHAVIOR. - ISSN 1525-5050. - STAMPA. - 37:Aug.(2014), pp. 87-90. [10.1016/j.yebeh.2014.06.012] | |
Handle: | http://hdl.handle.net/11573/629316 | |
Appartiene alla tipologia: | 01a Articolo in rivista |
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