the aim of the study is to assess intrarenal arterial stiffness by Doppler ultrasound and examine the correlation with AD using heart rate variability (HRV) analysis.The analysis of HRV in our study shows that the autonomic nervous system plays a key role in determining and maintaining the mechanisms responsible for the features of vasoactive system in SSc patients. Any changes of the vascular bed result in its decreased compliance, increased stiffness and a further increase in vascular resistances. RI measures the intrarenal arterial elasticity and in our study shows a linear correlation with sympathetic activity.The sympathovagal balance expressed by the LF/HF ratio shows no nocturnal expected reduction and therefore in these patients the loss of the circadian rhythm with constant sympathetic hyperactivity correlates directly with renal RI.In conclusion, the HRV analysis may be a useful screening tool for the early assessment of cardiovascular risk in patients with scleroderma.

Autonomic dysfunction in patients with systemic sclerosis: Correlation with intrarenal arterial stiffness / Gigante, Antonietta; Rosato, Edoardo; Liberatori, Marta; Barbano, Biagio; Cianci, Rosario; GASPERINI ZACCO, MARIA LUDOVICA; L., Sardo; A. M., Marra; Amoroso, Antonio; Salsano, Felice; A., Fiorentini; Tubani, Luigi. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - STAMPA. - 177:(2014), pp. 578-580. [10.1016/j.ijcard.2014.08.122]

Autonomic dysfunction in patients with systemic sclerosis: Correlation with intrarenal arterial stiffness

GIGANTE, ANTONIETTA;ROSATO, Edoardo;LIBERATORI, MARTA;BARBANO, BIAGIO;CIANCI, ROSARIO;GASPERINI ZACCO, MARIA LUDOVICA;AMOROSO, Antonio;SALSANO, Felice;TUBANI, Luigi
2014

Abstract

the aim of the study is to assess intrarenal arterial stiffness by Doppler ultrasound and examine the correlation with AD using heart rate variability (HRV) analysis.The analysis of HRV in our study shows that the autonomic nervous system plays a key role in determining and maintaining the mechanisms responsible for the features of vasoactive system in SSc patients. Any changes of the vascular bed result in its decreased compliance, increased stiffness and a further increase in vascular resistances. RI measures the intrarenal arterial elasticity and in our study shows a linear correlation with sympathetic activity.The sympathovagal balance expressed by the LF/HF ratio shows no nocturnal expected reduction and therefore in these patients the loss of the circadian rhythm with constant sympathetic hyperactivity correlates directly with renal RI.In conclusion, the HRV analysis may be a useful screening tool for the early assessment of cardiovascular risk in patients with scleroderma.
2014
systemic sclerosis; renal resistive index; heart rate variability; autonomic system
01 Pubblicazione su rivista::01a Articolo in rivista
Autonomic dysfunction in patients with systemic sclerosis: Correlation with intrarenal arterial stiffness / Gigante, Antonietta; Rosato, Edoardo; Liberatori, Marta; Barbano, Biagio; Cianci, Rosario; GASPERINI ZACCO, MARIA LUDOVICA; L., Sardo; A. M., Marra; Amoroso, Antonio; Salsano, Felice; A., Fiorentini; Tubani, Luigi. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - STAMPA. - 177:(2014), pp. 578-580. [10.1016/j.ijcard.2014.08.122]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/626023
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 22
  • ???jsp.display-item.citation.isi??? 23
social impact