Tuberculosis is a cronic granulomatosis infectious disease ,usually caused by Mycobacterium Tuberculosis; the infection is spread through Pflugge droplets from nose and mouth of infected patients; bacillus tuberculosis colonizes skin through exogenous or endogenous infection. The primary infection, rarely, causes disease in people not immunocompromised, as the specific immune response is able to containe mycobacterium inside granulomas and tubercles; however when we have an immunodepression condition mycobacteris can get worsed. Skin tuberculosis is a rare clinic condition; however for increase of pulmonary diseases we have a recrudescence of dermatologic disease, in industrialized countries, caused by the increase of people migration, by the resistance to antituberculosis drugs, by the active infection in HIV people and recently by the diffusion of biologic drugs. The authors present a case of papulonecrotic tuberculid in a Philippine woman, already on antituberculosis treatment.
La tubercolosi è una malattia infettiva cronica granulomatosa, causata solitamente dal Mycobacterium Tuberculosis; l’infezione si contrae solitamente tramite le goccioline di Pflugge emesse dai pazienti infetti; la cute viene colonizzata dai bacilli per infezione esogena o endogena. L’infezione primaria solo eccezionalmente è causa di malattia in soggetti con immunità cellulare intatta, in quanto la risposta immunitaria specifica riesce a contenere i micobatteri all’interno dei granulomi o tubercoli; tuttavia in condizioni di immunodepressione, i micobatteri possono riattivarsi. La tubercolosi cutanea è una condizione clinica rara; tuttavia, a causa dell’aumenta incidenza della malattia polmonare, stiamo assistendo ad una recrudescenza anche della malattia dermatologica, giustificata, nei paesi industrializzati, dalla più frequente migrazione delle popolazioni, dalla resistenza ai polichemioterapici antitubercolari, dallo sviluppo dell’infezione in soggetti HIV-positivi e dalla recente diffusione dei farmaci biologici.Gli autori presentano un caso di tuberculide papulonecrotica insorta in una donna, originaria delle Filippine, già in trattamento antitubercolare.
Un caso di tuberculide papulonecrotica / Pala, Salvatore; Carlesimo, Sandra Cinzia; Melis, Luca; Spataro, Anna; L., Mistrulli. - In: ESPERIENZE DERMATOLOGICHE. - ISSN 1128-9155. - STAMPA. - 14:1(2012), pp. 1-4.
Un caso di tuberculide papulonecrotica
PALA, Salvatore;CARLESIMO, Sandra Cinzia;MELIS, LUCA;SPATARO, ANNA;
2012
Abstract
Tuberculosis is a cronic granulomatosis infectious disease ,usually caused by Mycobacterium Tuberculosis; the infection is spread through Pflugge droplets from nose and mouth of infected patients; bacillus tuberculosis colonizes skin through exogenous or endogenous infection. The primary infection, rarely, causes disease in people not immunocompromised, as the specific immune response is able to containe mycobacterium inside granulomas and tubercles; however when we have an immunodepression condition mycobacteris can get worsed. Skin tuberculosis is a rare clinic condition; however for increase of pulmonary diseases we have a recrudescence of dermatologic disease, in industrialized countries, caused by the increase of people migration, by the resistance to antituberculosis drugs, by the active infection in HIV people and recently by the diffusion of biologic drugs. The authors present a case of papulonecrotic tuberculid in a Philippine woman, already on antituberculosis treatment.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.