The detection of the use of nandrolone and other 19-norsteroids is based primarily upon the identification of the main urinary metabolite, 19-norandrosterone (19-NA) in a concentration (derived from hydrolysis with β-glucuronidase) greater than the Decision Limit (DL), as established in the DL Technical Document. The presence of 19-NA in urine samples can be originated by: -the external administration of nandrolone or nandrolone precursor (as pharmaceutical or dietary formulation, progestogens, wild boar meat consumption); -the endogenous productions under particular physiological conditions (ovulation, pregnancy); -The ex-vivo production in urine by in-situ 19-demethylation of androsterone (A) (active urines)
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Titolo: | In-situ steroids 19-demethylation vs. aromatization | |
Autori: | ||
Data di pubblicazione: | 2013 | |
Handle: | http://hdl.handle.net/11573/615588 | |
ISBN: | 978-3-86884-039-1 | |
Appartiene alla tipologia: | 04b Atto di convegno in volume |