The introduction of highly active antiretroviral therapy (HAART) has reduced mortality and improved life expectancy of HIV-positive patients. However, increased survival is associated with increased prevalence of comorbidities, such as cardiovascular disease, hepatic and renal disease. Kidney disease, including HIV-associated nephropathy, acute renal failure and chronic kidney disease, represents one of the main causes of morbidity and mortality, especially if associated to other risk factors, i.e. hypertension, diabetes, older age, black race and hepatitis C coinfection. Careful evaluation of renal function may help identifying kidney disease in its early stages. In addition, proper management of hypertension and diabetes is recommended. Even if HAART has changed the natural course of HIV-associated nephropathy, reducing the risk of End-stage Renal Disease (ERDS), some antiretroviral regimens have been related with the development of acute or chronic kidney disease. Further studies are needed to optimize the management of renal disease among HIV-infected patients.

Kidney disease in HIV-infected patients / M. 1., Scarpino; M. R., Pinzone; M., Di Rosa; G., Madeddu; E., Foca; F., Martellotta; O., Schioppa; Ceccarelli, Giancarlo; B. M., Celesia; D'Ettorre, Gabriella; Vullo, Vincenzo; S., Berretta; B., Cacopardo; G., Nunnari. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 1128-3602. - ELETTRONICO. - 17:19(2013), pp. 2660-2667.

Kidney disease in HIV-infected patients

CECCARELLI, GIANCARLO;D'ETTORRE, Gabriella;VULLO, Vincenzo;
2013

Abstract

The introduction of highly active antiretroviral therapy (HAART) has reduced mortality and improved life expectancy of HIV-positive patients. However, increased survival is associated with increased prevalence of comorbidities, such as cardiovascular disease, hepatic and renal disease. Kidney disease, including HIV-associated nephropathy, acute renal failure and chronic kidney disease, represents one of the main causes of morbidity and mortality, especially if associated to other risk factors, i.e. hypertension, diabetes, older age, black race and hepatitis C coinfection. Careful evaluation of renal function may help identifying kidney disease in its early stages. In addition, proper management of hypertension and diabetes is recommended. Even if HAART has changed the natural course of HIV-associated nephropathy, reducing the risk of End-stage Renal Disease (ERDS), some antiretroviral regimens have been related with the development of acute or chronic kidney disease. Further studies are needed to optimize the management of renal disease among HIV-infected patients.
2013
arf; hiv; haart; hivan; ckd; kidney
01 Pubblicazione su rivista::01a Articolo in rivista
Kidney disease in HIV-infected patients / M. 1., Scarpino; M. R., Pinzone; M., Di Rosa; G., Madeddu; E., Foca; F., Martellotta; O., Schioppa; Ceccarelli, Giancarlo; B. M., Celesia; D'Ettorre, Gabriella; Vullo, Vincenzo; S., Berretta; B., Cacopardo; G., Nunnari. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 1128-3602. - ELETTRONICO. - 17:19(2013), pp. 2660-2667.
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/610214
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 13
  • Scopus 43
  • ???jsp.display-item.citation.isi??? 43
social impact