We report a rare case of a patient with AL amyloidosis and pseudoxanthoma elasticum skin lesions. An association between these two diseases has been previously described as amyloid elastosis in only six cases, but cardiac findings were not fully elucidated. The peculiarity of our case is that a severe cardiac involvement influenced the prognosis negatively. Furthermore, the electron microscopic examination did not show all the peculiar histopathological findings of amyloid elastosis, precluding a final diagnosis of this disease.
We report a rare case of a patient with AL amyloidosis and pseudoxanthoma elasticum skin lesions. An association between these two diseases has been previously described as amyloid elastosis in only six cases, but cardiac findings were not fully elucidated. The peculiarity of our case is that a severe cardiac involvement influenced the prognosis negatively. Furthermore, the electron microscopic examination did not show all the peculiar histopathological findings of amyloid elastosis, precluding a final diagnosis of this disease.
Restrictive cardiomyopathy and pseudoxanthoma elasticum skin lesions / Musumeci, Maria Beatrice; Semprini, Lorenzo; Casenghi, Matteo; Dalma, Montesanti; Mastromarino, Vittoria; Fabio, Socciarelli; Volpe, Massimo; Autore, Camillo. - In: JOURNAL OF CARDIOVASCULAR MEDICINE. - ISSN 1558-2027. - STAMPA. - (2014), p. 1. [10.2459/jcm.0000000000000158]
Restrictive cardiomyopathy and pseudoxanthoma elasticum skin lesions.
MUSUMECI, Maria Beatrice;SEMPRINI, LORENZO;CASENGHI, MATTEO;MASTROMARINO, VITTORIA;VOLPE, Massimo;AUTORE, Camillo
2014
Abstract
We report a rare case of a patient with AL amyloidosis and pseudoxanthoma elasticum skin lesions. An association between these two diseases has been previously described as amyloid elastosis in only six cases, but cardiac findings were not fully elucidated. The peculiarity of our case is that a severe cardiac involvement influenced the prognosis negatively. Furthermore, the electron microscopic examination did not show all the peculiar histopathological findings of amyloid elastosis, precluding a final diagnosis of this disease.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
