This prospective case-control study suggests that monocyte value is both an inexpensive and easy thrombosis criterion: the value above 500 cells/mm3 correlates with thrombosis at the onset and the value below 400 cells/mm3 correlates with restoration of vessel patency; moreover this difference is similar as that observed with d-Dimer value. However, it is interesting to notice that the d-Dimer rate of change does not correlate proportionally with the restoration of the vessel patency. In addition to this, the d-Dimer mean values are affected by an high error. After checking equipment and procedures to eliminate any potential source of systematic error, measurements of d-Dimer were repeated on the same specimens. However, the great variability of the measured values did not change, suggesting that the d-Dimer does not correlate with the pathology. Further study should analyze a third variable, in conjunction with d-Dimer and monocytes. This third parameter should be a factor well recognized as independent from DTV/PE as much as possible. The variability of this third variable should be affected by variability as well as the d-Dimer
Monocyte value could be a thrombosis marker? / Cafolla, Arturo. - In: THROMBOSIS RESEARCH. - ISSN 0049-3848. - STAMPA. - 133 Supplement 3 Thrombosis Research:(2014), pp. 95-95. (Intervento presentato al convegno 23th Biennal International Congress on thrombosis- MLTD Congress 2014 tenutosi a Valencia, Spain nel 14-17 May 2014) [doi:10.1016/S0049-3848(14)50306-4].
Monocyte value could be a thrombosis marker?
CAFOLLA, Arturo
2014
Abstract
This prospective case-control study suggests that monocyte value is both an inexpensive and easy thrombosis criterion: the value above 500 cells/mm3 correlates with thrombosis at the onset and the value below 400 cells/mm3 correlates with restoration of vessel patency; moreover this difference is similar as that observed with d-Dimer value. However, it is interesting to notice that the d-Dimer rate of change does not correlate proportionally with the restoration of the vessel patency. In addition to this, the d-Dimer mean values are affected by an high error. After checking equipment and procedures to eliminate any potential source of systematic error, measurements of d-Dimer were repeated on the same specimens. However, the great variability of the measured values did not change, suggesting that the d-Dimer does not correlate with the pathology. Further study should analyze a third variable, in conjunction with d-Dimer and monocytes. This third parameter should be a factor well recognized as independent from DTV/PE as much as possible. The variability of this third variable should be affected by variability as well as the d-DimerI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.