Borderline personality disorder is mainly characterized by instability of self-esteem interpersonal relations and mood. The tendency to react to frustrations with acting outs suggests the presence in such patients of a difficulty in the simbolising process, that does not allow a correct "mentalization" and therefore the attribution of a meaning to the stressful events. Several neurobiological studies of borderline personality disorder show a pattern characterised by ipoactivity of frontal and pre-frontal areas and a malfunctioning of amygdala. We performed Single Photo Emission Tomography (SPECT), using a video emotional activation paradigm, in a patient with borderline personality disorder and a control subject. Faced with violent scenes in the video, the patient, but not the control subject, showed an activation of limbic areas and prefrontal cortex. This activation pattern may be the neurobiological correlate of a cognitive activity put in action in order to manage the strong emotion triggered by the video, absent in the control subject.
Spect video emotional activation paradigm on borderline personality disorder: a pilot study / Lai, Carlo; S., Daini; M. L., Calcagni; F., Cirillo; S., DE RISIO. - In: WORLD PSYCHIATRY. - ISSN 1723-8617. - STAMPA. - 3 Supplement 1:(2004), pp. 329-329. (Intervento presentato al convegno International Conference of WPA (World Psychiatry Association) tenutosi a Firenze nel 4-10 Novembre 2004).
Spect video emotional activation paradigm on borderline personality disorder: a pilot study
LAI, CARLO;
2004
Abstract
Borderline personality disorder is mainly characterized by instability of self-esteem interpersonal relations and mood. The tendency to react to frustrations with acting outs suggests the presence in such patients of a difficulty in the simbolising process, that does not allow a correct "mentalization" and therefore the attribution of a meaning to the stressful events. Several neurobiological studies of borderline personality disorder show a pattern characterised by ipoactivity of frontal and pre-frontal areas and a malfunctioning of amygdala. We performed Single Photo Emission Tomography (SPECT), using a video emotional activation paradigm, in a patient with borderline personality disorder and a control subject. Faced with violent scenes in the video, the patient, but not the control subject, showed an activation of limbic areas and prefrontal cortex. This activation pattern may be the neurobiological correlate of a cognitive activity put in action in order to manage the strong emotion triggered by the video, absent in the control subject.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
