Our aim was to assess the velocimetric pattern of the ovarian artery as a possible marker of LH surge in stimulated cycles. A total of 130 women undergoing ovarian stimulation for intrauterine insemination were randomized in two groups. Each woman was stimulated with 75IU of recombinant FSH starting from the third day of the cycle. Velocimetric indices of the dominant ovarian artery were compared between patients with spontaneous LH surge and those needing HCG administration to trigger dominant follicle rupture. The pulsatility index and the ratio between peak systolic flow and lowest diastolic flow were significantly higher in women that had a spontaneous triggering of ovulation. These parameters had a high and very significant positive correlation with the dosage of luteinizing hormone. Threshold values of 2.60 for PI and 7.68 for S/D had a high sensitivity and specificity to predict LH surge. These velocimetric results demonstrated that an increased resistance in the dominant ovarian artery is correlated to LH surge in stimulated cycles. It may represent a sign of relevant clinical utility in timing of intrauterine insemination and/or natural intercourse. © 2014 Informa UK Ltd. All rights reserved.

Doppler velocimetry of the ovarian artery as a tool to detect LH surge in stimulated cycles / Giugliano, Emilio; Elisa, Cagnazzo; Fortunato, Vesce; Brunella, Giugliano; Caserta, Donatella; Moscarini, Massimo; Carola, Caldarelli; Giancarlo, Stellin; Roberto, Marci. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - STAMPA. - 30:9(2014), pp. 627-631. [10.3109/09513590.2014.911276]

Doppler velocimetry of the ovarian artery as a tool to detect LH surge in stimulated cycles

GIUGLIANO, EMILIO;CASERTA, Donatella;MOSCARINI, Massimo;
2014

Abstract

Our aim was to assess the velocimetric pattern of the ovarian artery as a possible marker of LH surge in stimulated cycles. A total of 130 women undergoing ovarian stimulation for intrauterine insemination were randomized in two groups. Each woman was stimulated with 75IU of recombinant FSH starting from the third day of the cycle. Velocimetric indices of the dominant ovarian artery were compared between patients with spontaneous LH surge and those needing HCG administration to trigger dominant follicle rupture. The pulsatility index and the ratio between peak systolic flow and lowest diastolic flow were significantly higher in women that had a spontaneous triggering of ovulation. These parameters had a high and very significant positive correlation with the dosage of luteinizing hormone. Threshold values of 2.60 for PI and 7.68 for S/D had a high sensitivity and specificity to predict LH surge. These velocimetric results demonstrated that an increased resistance in the dominant ovarian artery is correlated to LH surge in stimulated cycles. It may represent a sign of relevant clinical utility in timing of intrauterine insemination and/or natural intercourse. © 2014 Informa UK Ltd. All rights reserved.
2014
artificial insemination; doppler color ultrasonography; female infertility; luteinizing hormone; ovulation
01 Pubblicazione su rivista::01a Articolo in rivista
Doppler velocimetry of the ovarian artery as a tool to detect LH surge in stimulated cycles / Giugliano, Emilio; Elisa, Cagnazzo; Fortunato, Vesce; Brunella, Giugliano; Caserta, Donatella; Moscarini, Massimo; Carola, Caldarelli; Giancarlo, Stellin; Roberto, Marci. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - STAMPA. - 30:9(2014), pp. 627-631. [10.3109/09513590.2014.911276]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/579379
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact