Vernal keratoconjunctivitis has been considered a multifac- torial condition resulting from complex interactions among genetic, immunologic, and environmental factors. The research of genetic characteristics and the identification of a specific HLA haplotype as a possible predictor of disease may contribute to elucidate the pathogenesis of the disease and to point out the VKC as a complex immunologic disorder rather than as a mere allergic disease. The identification of a specific haplotype associated with VKC might be helpful to identify children predisposed to develop this ocular disease and patients with a specific outcome.
Immunogenetic investigation in vernal keratoconjunctivitis / Zicari, Anna Maria; Barbara, Mora; Valeria, Lollobrigida; Occasi, Francesca; Azzurra, Cesoni; Megiorni, Francesca; Pizzuti, Antonio; Nebbioso, Marcella; Duse, Marzia. - In: PEDIATRIC ALLERGY AND IMMUNOLOGY. - ISSN 0905-6157. - STAMPA. - 25:5(2014), pp. 508-510. [10.1111/pai.12231]
Immunogenetic investigation in vernal keratoconjunctivitis
ZICARI, Anna Maria;OCCASI, FRANCESCA;Francesca Megiorni;PIZZUTI, Antonio;NEBBIOSO, Marcella;DUSE, MARZIA
2014
Abstract
Vernal keratoconjunctivitis has been considered a multifac- torial condition resulting from complex interactions among genetic, immunologic, and environmental factors. The research of genetic characteristics and the identification of a specific HLA haplotype as a possible predictor of disease may contribute to elucidate the pathogenesis of the disease and to point out the VKC as a complex immunologic disorder rather than as a mere allergic disease. The identification of a specific haplotype associated with VKC might be helpful to identify children predisposed to develop this ocular disease and patients with a specific outcome.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
