Immediate loading of post-extractive single-tooth implants: a 1-year prospective study.

Purpose: The aim of this prospective clinical trial was to assess clinical, radiological, and esthetic outcomes of immediate-loaded post-extractive implants after 1 year of follow-up. Materials and Methods: Twenty-four consecutive patients (15 females and nine males) with a mean age of 47.27 years (range 35-65) requiring single-tooth extraction in the maxillary or mandibular anterior or premolar areas were enrolled. Twenty-five NobelActive® implants (Nobel Biocare, Göteborg, Sweden) were placed and loaded immediately after tooth extraction. The definitive prosthetic restoration was delivered 6 months later. Clinical parameters, marginal bone loss, as well as, pink and white esthetic scores (PES and WES) were evaluated at 3, 6, and 12 months after implant placement. Results: After 12-month follow-up period, a success rate of 91.67% was reported: Two of the 25 initially placed implants were lost after 4 weeks due to lack of osseointegration. The mean marginal bone loss after 1-year follow-up was 0.383 (SD ± 0.749) at mesial site and 0.278 (SD ± 0.595) at distal site. No statistically significant changes in the full-mouth plaque score (FMPS) and in the full-mouth bleeding score (FMBS) were observed from baseline to 12 months. The mean total PES/WES was 17.13 ± 1.91 (range: 13-20). None of 23 implants had an overall score <12 (threshold of clinical acceptability). Conclusion: Within the limitations of the present study, when careful patient selection and strict clinical protocol are observed, the immediate placement and loading of a single NobelActive™ implant in a fresh extraction socket may be considered a valuable and predictable option in terms of implant success as well as hard and soft tissues stability. © 2014 John Wiley & Sons A/S.