Carcinoma ex pleomorphic adenoma is a rare tumor arising from the salivary glands that spreads through direct extension, through the lymphatic vessels, and, rarely, hematogenously. When distant metastases have been found, they have been reported mainly in the lung. We present an unusual case of carcinoma ex pleomorphic adenoma of the parotid gland with splenic metastases. The patient presented with a primary carcinoma ex pleomorphic adenoma of the parotid gland and he underwent a total parotidectomy with laterocervical lymphadenectomy ipsilateral and adjuvant radiation therapy to the right parotid area. One year later, the patient showed an ipsilateral supraclavicular lymph node recurrence, treated with surgery and radiation therapy. Two more years later, the patient developed lung and splenic lesions, detected through CT and PET. He underwent splenectomy and pathologic assessment of the specimen showed metastatic carcinoma ex pleomorphic adenoma. To our knowledge, there is no reported case of a carcinoma ex pleomorphic adenoma metastasizing to the spleen. Patients treated for carcinoma ex pleomorphic adenoma should be investigated for distant metastases with a long-term follow-up examination for local and distant metastases and new splenic lesions in these patients should be investigated. © 2014 Rossi et al.; licensee BioMed Central Ltd.

An unusual case of spleen metastasis from carcinoma ex pleomorphic adenoma of the parotid gland / Rossi, Luigi; Giordani, Erika; Antonella, Fontana; DI CRISTOFANO, Claudio; Cavallaro, Giuseppe; Oreste, Bagni; Luca, Filippi; Loredana, Bianchi; Giulia, Rinaldi; Francesca, Congedi; Papa, Anselmo; Caruso, Davide; Verrico, Monica; Silecchia, Gianfranco; Tomao, Silverio. - In: WORLD JOURNAL OF SURGICAL ONCOLOGY. - ISSN 1477-7819. - STAMPA. - 12:1(2014). [10.1186/1477-7819-12-18]

An unusual case of spleen metastasis from carcinoma ex pleomorphic adenoma of the parotid gland

ROSSI, Luigi;GIORDANI, ERIKA;DI CRISTOFANO, CLAUDIO;CAVALLARO, Giuseppe;PAPA, ANSELMO;CARUSO, DAVIDE;VERRICO, MONICA;SILECCHIA, Gianfranco;TOMAO, SILVERIO
2014

Abstract

Carcinoma ex pleomorphic adenoma is a rare tumor arising from the salivary glands that spreads through direct extension, through the lymphatic vessels, and, rarely, hematogenously. When distant metastases have been found, they have been reported mainly in the lung. We present an unusual case of carcinoma ex pleomorphic adenoma of the parotid gland with splenic metastases. The patient presented with a primary carcinoma ex pleomorphic adenoma of the parotid gland and he underwent a total parotidectomy with laterocervical lymphadenectomy ipsilateral and adjuvant radiation therapy to the right parotid area. One year later, the patient showed an ipsilateral supraclavicular lymph node recurrence, treated with surgery and radiation therapy. Two more years later, the patient developed lung and splenic lesions, detected through CT and PET. He underwent splenectomy and pathologic assessment of the specimen showed metastatic carcinoma ex pleomorphic adenoma. To our knowledge, there is no reported case of a carcinoma ex pleomorphic adenoma metastasizing to the spleen. Patients treated for carcinoma ex pleomorphic adenoma should be investigated for distant metastases with a long-term follow-up examination for local and distant metastases and new splenic lesions in these patients should be investigated. © 2014 Rossi et al.; licensee BioMed Central Ltd.
parotid tumours; pleomorphic adenoma; splenic metastases; carcinoma ex pleomorphic adenoma
01 Pubblicazione su rivista::01a Articolo in rivista
An unusual case of spleen metastasis from carcinoma ex pleomorphic adenoma of the parotid gland / Rossi, Luigi; Giordani, Erika; Antonella, Fontana; DI CRISTOFANO, Claudio; Cavallaro, Giuseppe; Oreste, Bagni; Luca, Filippi; Loredana, Bianchi; Giulia, Rinaldi; Francesca, Congedi; Papa, Anselmo; Caruso, Davide; Verrico, Monica; Silecchia, Gianfranco; Tomao, Silverio. - In: WORLD JOURNAL OF SURGICAL ONCOLOGY. - ISSN 1477-7819. - STAMPA. - 12:1(2014). [10.1186/1477-7819-12-18]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/555922
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