I have read with great interest the article by Davis AP et al. on early diagnosis and treatment of obstructive sleep apnea (OSA) after stroke. In the article Authors exhaustively argued the negative prognostic role of OSA on stroke clinical outcome and on its recurrence, as well as evidences on the positive effect of CPAP on patients’ outcome. The reasons for patients’ adherence to CPAP treatment were instead too much simplified. Authors neglected that some pathophysiological mechanisms responsible for SDB, such as a high loop gain, can be responsible for patients’ unresponsiveness to CPAP 1. In fact, a central sleep apnea-hypopnea (CSAH) can be detected in cases with obstructive sleep apnea-hypopnea (OSAH) when are treated with CPAP 2. This phenomenon has been reported to occur in stroke patients, and can verify spontaneously in patients with congestive heart failure (CHF) 3. Since CPAP treatment of stroke cases has given inconclusive results, the question rises whether clinical and/o

Early diagnosis and treatment of obstructive sleep apnea after stroke: Are we neglecting a modifiable stroke risk factor? / Sacchetti, Maria Luisa. - In: NEUROLOGY. CLINICAL PRACTICE. - ISSN 2163-0402. - ELETTRONICO. - 3:5(2013), pp. 369-371. [10.1212/CPJ.0b013e318296f274]

Early diagnosis and treatment of obstructive sleep apnea after stroke: Are we neglecting a modifiable stroke risk factor?

SACCHETTI, Maria Luisa
2013

Abstract

I have read with great interest the article by Davis AP et al. on early diagnosis and treatment of obstructive sleep apnea (OSA) after stroke. In the article Authors exhaustively argued the negative prognostic role of OSA on stroke clinical outcome and on its recurrence, as well as evidences on the positive effect of CPAP on patients’ outcome. The reasons for patients’ adherence to CPAP treatment were instead too much simplified. Authors neglected that some pathophysiological mechanisms responsible for SDB, such as a high loop gain, can be responsible for patients’ unresponsiveness to CPAP 1. In fact, a central sleep apnea-hypopnea (CSAH) can be detected in cases with obstructive sleep apnea-hypopnea (OSAH) when are treated with CPAP 2. This phenomenon has been reported to occur in stroke patients, and can verify spontaneously in patients with congestive heart failure (CHF) 3. Since CPAP treatment of stroke cases has given inconclusive results, the question rises whether clinical and/o
2013
stroke; sleep apnea
01 Pubblicazione su rivista::01b Commento, Erratum, Replica e simili
Early diagnosis and treatment of obstructive sleep apnea after stroke: Are we neglecting a modifiable stroke risk factor? / Sacchetti, Maria Luisa. - In: NEUROLOGY. CLINICAL PRACTICE. - ISSN 2163-0402. - ELETTRONICO. - 3:5(2013), pp. 369-371. [10.1212/CPJ.0b013e318296f274]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/555582
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