Computer-aided drug design techniques have become an integral part of the drug discovery process. In particular, de novo methodologies can be useful to identify putative ligands for a specific target relying only on the structural information of the target itself. Here we discuss the basic de novo approaches available and their application in antiviral drug design.
De novo computer-aided design of novel antiviral agents / Massarotti, A.; Coluccia, Antonio; Sorba, G.; Silvestri, Romano; Brancale, A.. - In: DRUG DISCOVERY TODAY. - ISSN 1359-6446. - 9:(2012), pp. 213-218. [10.1016/j.ddtec.2011.11.008]
De novo computer-aided design of novel antiviral agents.
COLUCCIA, Antonio;SILVESTRI, Romano;
2012
Abstract
Computer-aided drug design techniques have become an integral part of the drug discovery process. In particular, de novo methodologies can be useful to identify putative ligands for a specific target relying only on the structural information of the target itself. Here we discuss the basic de novo approaches available and their application in antiviral drug design.File allegati a questo prodotto
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