In heart failure (HF), the progressive use of multiple drugs and a complex therapeutic regimen is common and is recommended by international guidelines.With HF being a common disease in the elderly, patients often have numerous comorbidities that require additional specific treatment, thus producing a heavy pill burden. Polypharmacy, defined as the chronic use of five or more medications, is an underestimated problem in the management of HF patients. However, polypharmacy has an important impact on HF treatment, as it often leads to inappropriate drug prescription, poor adherence to pharmacological therapies, drug-drug interactions, and adverse effects. The growing complexity of HF patients, whose mean age increases progressively and who present multiple comorbidities, suggests the need for newer models of primary care to improve the management of HF patients. Self-care, telemonitoring, and natriuretic peptide-guided therapy represent promising new HF care models to face the complexity of the disease and its therapeutic regimen. © Springer Science+Business Media 2014.

Polypharmacy in Heart Failure Patients / Mastromarino, Vittoria; Casenghi, Matteo; Marco, Testa; Erica, Gabriele; Coluccia, Roberta; Rubattu, Speranza Donatella; Volpe, Massimo. - In: CURRENT HEART FAILURE REPORTS. - ISSN 1546-9530. - 11:2(2014), pp. 212-219. [10.1007/s11897-014-0186-8]

Polypharmacy in Heart Failure Patients

MASTROMARINO, VITTORIA;CASENGHI, MATTEO;COLUCCIA, ROBERTA;RUBATTU, Speranza Donatella;VOLPE, Massimo
2014

Abstract

In heart failure (HF), the progressive use of multiple drugs and a complex therapeutic regimen is common and is recommended by international guidelines.With HF being a common disease in the elderly, patients often have numerous comorbidities that require additional specific treatment, thus producing a heavy pill burden. Polypharmacy, defined as the chronic use of five or more medications, is an underestimated problem in the management of HF patients. However, polypharmacy has an important impact on HF treatment, as it often leads to inappropriate drug prescription, poor adherence to pharmacological therapies, drug-drug interactions, and adverse effects. The growing complexity of HF patients, whose mean age increases progressively and who present multiple comorbidities, suggests the need for newer models of primary care to improve the management of HF patients. Self-care, telemonitoring, and natriuretic peptide-guided therapy represent promising new HF care models to face the complexity of the disease and its therapeutic regimen. © Springer Science+Business Media 2014.
2014
adherence; polypharmacy; comorbidities; heart failure; brain natriuretic peptide; self-care
01 Pubblicazione su rivista::01a Articolo in rivista
Polypharmacy in Heart Failure Patients / Mastromarino, Vittoria; Casenghi, Matteo; Marco, Testa; Erica, Gabriele; Coluccia, Roberta; Rubattu, Speranza Donatella; Volpe, Massimo. - In: CURRENT HEART FAILURE REPORTS. - ISSN 1546-9530. - 11:2(2014), pp. 212-219. [10.1007/s11897-014-0186-8]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/554284
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 34
  • Scopus 57
  • ???jsp.display-item.citation.isi??? ND
social impact