The long-term (18 months) oeular tension-Iowering effeet of brinzolarnide, a topieal earbonic anhydrase inhibitor reeently introdueed in the antiglaucomatous treatment, in 50 patients suffering from Open-angle Glaucoma was evaluated. Following one-month treatment a reduction in IOP of 22% was already observed in 81 % of the eyes examined. Such reduction was maintained throughout the observation time. In I 1% of cases topical side-effects were observed and treatment was diseontinued. In 8% of the eyes the drug was shown to be unable to control IOP. Brinzolamide represents a valuable alternative in the antiglaucomatous therapy.
È stata valutata razione ipotensiva oculare a lungo termine (18 mesi) della brinzolamide, un inibitore dell' anidrasi carbonica di recente introduzione in terapia, in 50 pazienti affetti da GAA. È stata riscontrata già dal primo mese una riduzione del 20.84% della IOP nell'81 % degli occhi esaminati che si è mantenuta costante per la durata dell'osservazione. Nell' Il % dei casi si sono verificati effetti collaterali locali e sistemici. Nell' 8ge degli occhi il farmaco si è dimostrato inefficace. Pertanto la brinzolamide rappresenta una valida alternativa nel trattamento del GAA.
La brinzolamide come valida terapia sostitutiva nel glaucoma ad angolo aperto / J., Pecori Giraldi; Librando, Aloisa; A., Mollicone; A., Gabrielli. - In: BOLLETTINO DI OCULISTICA. - ISSN 0006-677X. - STAMPA. - 81:5/6(2002), pp. 21-26.
La brinzolamide come valida terapia sostitutiva nel glaucoma ad angolo aperto
LIBRANDO, Aloisa;
2002
Abstract
The long-term (18 months) oeular tension-Iowering effeet of brinzolarnide, a topieal earbonic anhydrase inhibitor reeently introdueed in the antiglaucomatous treatment, in 50 patients suffering from Open-angle Glaucoma was evaluated. Following one-month treatment a reduction in IOP of 22% was already observed in 81 % of the eyes examined. Such reduction was maintained throughout the observation time. In I 1% of cases topical side-effects were observed and treatment was diseontinued. In 8% of the eyes the drug was shown to be unable to control IOP. Brinzolamide represents a valuable alternative in the antiglaucomatous therapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.