Numerical simulation of remodeling of bone tissue and bio-resorbable material mixture with voids under different loads

A model of a mixture of bone tissue and bio-resorbable material with voids was used to numerically analyze the physiological balance between the processes of bone growth and resorption and artificial material resorption in a plate-like sample. The adopted model was derived from a theory for the behavior of porous solids in which the matrix material is linearly elastic and the interstices are void of material. The specimen was constituted by a region of bone living tissue and one of bio-resorbable material and was acted by different in-plane loading conditions, namely pure bending and shear. Ranges of load magnitudes were identified within which physiological states become possible. A parametric analysis was worked out to evaluate the sensitivity of the model to changes of the constitutive parameters of material varying within physiological ranges.