A computational and vibrational spectroscopic study of the aqua complexes obtained by hydrolysis of cis-and trans-diamminedichloroplatinum(II) is reported. Electrospray ionization has allowed cis-and trans-[PtCl(NH 3)2(H2O)]+ species to be obtained as free ions in the gas phase where they were sampled by infrared multiple photon dissociation (IRMPD) spectroscopy in the NH/OH stretching frequency range (3200-3800 cm-1). The experimental features have been assigned by comparison with the linear IR spectra calculated for the optimized structures, revealing vibrational signatures characteristic of the two isomers. © 2013 American Chemical Society.
Vibrational signatures of the naked aqua complexes from platinum(II) anticancer drugs / DE PETRIS, Alberto; Ciavardini, Alessandra; C., Coletti; N., Re; Chiavarino, Barbara; Crestoni, Maria Elisa; Fornarini, Simonetta. - In: THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS. - ISSN 1948-7185. - ELETTRONICO. - 4:(2013), pp. 3631-3635. [10.1021/jz401959s]
Vibrational signatures of the naked aqua complexes from platinum(II) anticancer drugs
DE PETRIS, ALBERTO;CIAVARDINI, ALESSANDRA;CHIAVARINO, Barbara;CRESTONI, Maria Elisa;FORNARINI, Simonetta
2013
Abstract
A computational and vibrational spectroscopic study of the aqua complexes obtained by hydrolysis of cis-and trans-diamminedichloroplatinum(II) is reported. Electrospray ionization has allowed cis-and trans-[PtCl(NH 3)2(H2O)]+ species to be obtained as free ions in the gas phase where they were sampled by infrared multiple photon dissociation (IRMPD) spectroscopy in the NH/OH stretching frequency range (3200-3800 cm-1). The experimental features have been assigned by comparison with the linear IR spectra calculated for the optimized structures, revealing vibrational signatures characteristic of the two isomers. © 2013 American Chemical Society.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
