Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a previous endonasal transsphenoidal resection for a presumptive pituitary macroadenoma. Pituitary magnetic resonance imaging showed a tumor regrowth in the original location with a haemorrhagic component involving the left cavernous sinus. A near complete transsphenoidal resection of the sellar mass was performed followed by 3 months of stereotactic radiotherapy. Because of a worsening of the general clinical conditions, respiratory failure, and asthenia, the patient underwent a contrast enhanced computer tomography of the whole body which showed the presence of lung metastasis. The histopathological diagnosis on samples from pituitary and lung tissues was AT/RT. The patient survived 30 months after diagnosis regardless chemotherapy. In the adult, the AT/RT should be considered as a possible rare, aggressive, and malignant neoplasm localized in the sella turcica.

Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female / C., Moretti; D., Lupoi; F., Spasaro; L., Chioma; P., Di Giacinto; M., Colicchia; M., Frajoli; Mocini, Renzo; Ulisse, Salvatore; Antonelli, Manila; Giangaspero, Felice; Gnessi, Lucio. - In: CLINICAL MEDICINE INSIGHTS. CASE REPORTS. - ISSN 1179-5476. - ELETTRONICO. - 6:(2013), pp. 177-182. [10.4137/ccrep.s12834]

Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female

MOCINI, RENZO
Writing – Review & Editing
;
ULISSE, SALVATORE;ANTONELLI, MANILA;GIANGASPERO, FELICE;GNESSI, Lucio
2013

Abstract

Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a previous endonasal transsphenoidal resection for a presumptive pituitary macroadenoma. Pituitary magnetic resonance imaging showed a tumor regrowth in the original location with a haemorrhagic component involving the left cavernous sinus. A near complete transsphenoidal resection of the sellar mass was performed followed by 3 months of stereotactic radiotherapy. Because of a worsening of the general clinical conditions, respiratory failure, and asthenia, the patient underwent a contrast enhanced computer tomography of the whole body which showed the presence of lung metastasis. The histopathological diagnosis on samples from pituitary and lung tissues was AT/RT. The patient survived 30 months after diagnosis regardless chemotherapy. In the adult, the AT/RT should be considered as a possible rare, aggressive, and malignant neoplasm localized in the sella turcica.
2013
atypical teratoid/rhabdoid tumor (at/rt); lung; sella turcica; atypical teratoid/rhabdoid tumor; lung metastasis; metastasis; pituitary
01 Pubblicazione su rivista::01a Articolo in rivista
Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female / C., Moretti; D., Lupoi; F., Spasaro; L., Chioma; P., Di Giacinto; M., Colicchia; M., Frajoli; Mocini, Renzo; Ulisse, Salvatore; Antonelli, Manila; Giangaspero, Felice; Gnessi, Lucio. - In: CLINICAL MEDICINE INSIGHTS. CASE REPORTS. - ISSN 1179-5476. - ELETTRONICO. - 6:(2013), pp. 177-182. [10.4137/ccrep.s12834]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/533048
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