Although not life-threatening, vasomotor symptoms might have a detrimental effect on quality of life and represent a major determinant of poor therapeutic compliance in breast cancer patients. Limitations of hormonal therapies have fostered the use of non-estrogenic pharmacological agents, which mainly include centrally acting compounds, antidepressant drugs, serotonin-norepinephrine reuptake inhibitors and serotonin reuptake inhibitors. Integrating therapeutic tools have recently come from a wide range of heterogeneous approaches varying from phytoestrogens use to ganglion block. We herein critically review the most updated evidence on the available treatment options for management of vasomotor symptoms. The need for a patient-oriented approach following systematic evaluation of the presence and degree of vasomotor disturbances is also discussed and future perspectives in therapeutics are summarized. © Informa UK, Ltd.

Hot flushes in women with breast cancer: State of the art and future perspectives / Maddalena, Barba; Laura, Pizzuti; Domenico, Sergi; Marcello Maugeri, Sacca; Cristina, Vincenzoni; Francesca, Conti; Tomao, Federica; Enrico, Vizza; Luigi Di, Lauro; Franco Di, Filippo; Silvia, Carpano; Luciano, Mariani; Patrizia, Vici. - In: EXPERT REVIEW OF ANTICANCER THERAPY. - ISSN 1473-7140. - ELETTRONICO. - 14:2(2014), pp. 185-198. [10.1586/14737140.2013.856271]

Hot flushes in women with breast cancer: State of the art and future perspectives

TOMAO, FEDERICA;
2014

Abstract

Although not life-threatening, vasomotor symptoms might have a detrimental effect on quality of life and represent a major determinant of poor therapeutic compliance in breast cancer patients. Limitations of hormonal therapies have fostered the use of non-estrogenic pharmacological agents, which mainly include centrally acting compounds, antidepressant drugs, serotonin-norepinephrine reuptake inhibitors and serotonin reuptake inhibitors. Integrating therapeutic tools have recently come from a wide range of heterogeneous approaches varying from phytoestrogens use to ganglion block. We herein critically review the most updated evidence on the available treatment options for management of vasomotor symptoms. The need for a patient-oriented approach following systematic evaluation of the presence and degree of vasomotor disturbances is also discussed and future perspectives in therapeutics are summarized. © Informa UK, Ltd.
2014
breast cancer; hot flushes; breast cancer therapy; hot flashes; menopause; non-hormonal therapy; vasomotor symptoms; complementary and alternative medicine
01 Pubblicazione su rivista::01a Articolo in rivista
Hot flushes in women with breast cancer: State of the art and future perspectives / Maddalena, Barba; Laura, Pizzuti; Domenico, Sergi; Marcello Maugeri, Sacca; Cristina, Vincenzoni; Francesca, Conti; Tomao, Federica; Enrico, Vizza; Luigi Di, Lauro; Franco Di, Filippo; Silvia, Carpano; Luciano, Mariani; Patrizia, Vici. - In: EXPERT REVIEW OF ANTICANCER THERAPY. - ISSN 1473-7140. - ELETTRONICO. - 14:2(2014), pp. 185-198. [10.1586/14737140.2013.856271]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/526106
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 2
social impact