The methicillin-resistance is increasing all over the world in the last decade. It is more frequent among coagulase-negative staphylococci (MRCoNS) compared to Staphylococcus aureus: in fact the 52% of S. epidermidis strains results to be resistant to methicillin. The methicillin-resistant strains also show a reduced sensitivity towards the first-line agents such as glycopeptides and other antibiotics commonly used in therapy such as trimethoprim-sulphamethoxazole, imipenem , gentamycin , fosfomycin and chlarytromicin. Unlike MRSA (Methicillin-resistant S. aureus), MRCoNS resistance to glycopeptides generally concerns teicoplanin. Although vancomycin resistance is rare in Staphylococcus isolates, the detected shift towards higher values of MICs might affect patient's clinical outcome.
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Titolo: | Prevalence of methicillin-resistant Staphylococci isolated from different biological samples at Policlinico Umberto I° of Rome :correlation with vancomycin susceptibility |
Autori: | |
Data di pubblicazione: | 2011 |
Rivista: | |
Handle: | http://hdl.handle.net/11573/525292 |
Appartiene alla tipologia: | 01a Articolo in rivista |