ICU admittance prediction of the seventh-day organ dysfunction clustering

Organ dysfunction is usually evaluated by gravity scores (Logistic Organ Dysfunction Score, Multi-Organ Dysfunction Score and Sequential Organ Failure Assessment), aimed to predict the patient’s hospital outcome [1,2]. Despite their diffusion, these scores do not provide indications about the treatment’s efficacy for each patient. Our aim was to utilize the previous organ dysfunction scores to perform early strategies to preserve organ function. This study tested the following hypothesis: first, that the previous organ dysfunction scores can detect clustering of organ dysfunctions; second, that each clustering could have an own sequence; and, finally, that we can develop a model to predict from the scores at ICU admittance the organ dysfunctions after the seventh day.