Bullous morphea is an uncommon form of localized scleroderma. The pathogenesis is unknown and treatment of coexistent ulcers is difficult. The pathogenesis of bullae formation in morphea is multifactorial, but reactive oxygen species production appears to play a key role. We report a patient with bullous morphea with long-standing ulcers whom we successfully treated with N-acetylcysteine and topical wound care. N-acetylcysteine, an antioxidant sulfhydryl substance, promotes the healing of ulcers in patients with bullous morphea. Copyright © by BIOLIFE, s.a.s.
Ulcers caused by bullous morphea: Successful therapy with N-acetylcysteine and topical wound care / Rosato, Edoardo; M. L., Veneziano; A., Di Mario; I., Molinaro; Pisarri, Simonetta; Salsano, Felice. - In: INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY. - ISSN 0394-6320. - STAMPA. - 26:1(2013), pp. 259-262.
Ulcers caused by bullous morphea: Successful therapy with N-acetylcysteine and topical wound care
ROSATO, Edoardo;PISARRI, Simonetta;SALSANO, Felice
2013
Abstract
Bullous morphea is an uncommon form of localized scleroderma. The pathogenesis is unknown and treatment of coexistent ulcers is difficult. The pathogenesis of bullae formation in morphea is multifactorial, but reactive oxygen species production appears to play a key role. We report a patient with bullous morphea with long-standing ulcers whom we successfully treated with N-acetylcysteine and topical wound care. N-acetylcysteine, an antioxidant sulfhydryl substance, promotes the healing of ulcers in patients with bullous morphea. Copyright © by BIOLIFE, s.a.s.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
