Current evidence from the available clinical trials strongly support the notion that catheter-based radiofrequency ablation of renal nerves reduces blood pressure and improves blood pressure control in patients with drug-treated resistant hypertension, with data now extending out to 36 months. Accordingly, renal denervation can be considered as a therapeutic option in patients with resistant hypertension, whose blood pressure cannot be controlled by a combination of lifestyle modification and pharmacological therapy according to current guidelines. The fact that renal denervation also reduces whole-bodysympathetic nerve activity suggests that this therapy may also be beneficial in other clinical states characterized by sympathetic nervous system activation-this may ultimately lead to new indications. © The Author 2013.
Expert consensus document from the European Society of Cardiology on catheter-based renal denervation / F., M., T. F., L., B., A., I., B., R., C., C., D., P., D., R., F., J., F., M., K., T., L., C., L., H., S., Volpe, M., P., W., W., W., B., W., S., W., A., W., T., Z., et al.. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - STAMPA. - 34:28(2013), pp. 2149-2157. [10.1093/eurheartj/eht154]
Expert consensus document from the European Society of Cardiology on catheter-based renal denervation
VOLPE, Massimo;
2013
Abstract
Current evidence from the available clinical trials strongly support the notion that catheter-based radiofrequency ablation of renal nerves reduces blood pressure and improves blood pressure control in patients with drug-treated resistant hypertension, with data now extending out to 36 months. Accordingly, renal denervation can be considered as a therapeutic option in patients with resistant hypertension, whose blood pressure cannot be controlled by a combination of lifestyle modification and pharmacological therapy according to current guidelines. The fact that renal denervation also reduces whole-bodysympathetic nerve activity suggests that this therapy may also be beneficial in other clinical states characterized by sympathetic nervous system activation-this may ultimately lead to new indications. © The Author 2013.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
