Hypertensive nephrosclerosis is a much overused clinical diagnosis, largely unsubstantiated by biopsy data. It is in fact a clinical-pathological diagnosis implying a causal role of hypertension in the associated chronic kidney disease. However, such a simple, linear causality is often not obvious or easy to demonstrate. Further factors like age, Afro-American descent, genetic and immunological factors as well as dysmetabolic syndrome may contribute to the development and progression of arterionephrosclerosis independently of hypertension.
[Hypertensive nephrosclerosis: an exhaustive diagnosis?] / Malatino, L; Stancanelli, B; Giannakakis, Konstantinos; Marcantoni, C.. - In: GIORNALE ITALIANO DI NEFROLOGIA. - ISSN 0393-5590. - ELETTRONICO. - 29:(2012), pp. 650-654.
[Hypertensive nephrosclerosis: an exhaustive diagnosis?].
GIANNAKAKIS, Konstantinos;
2012
Abstract
Hypertensive nephrosclerosis is a much overused clinical diagnosis, largely unsubstantiated by biopsy data. It is in fact a clinical-pathological diagnosis implying a causal role of hypertension in the associated chronic kidney disease. However, such a simple, linear causality is often not obvious or easy to demonstrate. Further factors like age, Afro-American descent, genetic and immunological factors as well as dysmetabolic syndrome may contribute to the development and progression of arterionephrosclerosis independently of hypertension.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.