Thyroid disease is one of the most common endocrine conditions affecting women during reproductive age. A link between thyroid and assisted reproduction outcome is debated. Serum TSH levels, number and scoring of oocytes and embryos, and number of clinical pregnancies were retrospectively recorded in 164 women undergoing assisted reproduction technologies (ART) at an University-based fertility center, to evaluate the outcome of the first steps of assisted reproduction (ovarian stimulation, oocyte pickup and fertilization, embryo transfer and implantation) in relation to thyroid function and autoimmunity. No significant relationship was found between TSH and all parameters, except clinical pregnancy rate (22.3% in TSH ≤ 2.5 group versus 8.9% in TSH > 2.5 mUI/L group; P = 0.045). No pregnancy occurred in women with anti-thyroperoxidase autoantibodies, while pregnancy occurred in 23.9% of cycles without autoimmunity (P = 0.02). Further studies must be conducted in order to shed light on the link between infertility and thyroid dysfunction. © 2013 John Wiley & Sons Ltd.

Thyroid Function in Infertile Patients Undergoing Assisted Reproduction / Fumarola, Angela; Grani, Giorgio; Romanzi, Daniela; DEL SORDO, Marianna; Bianchini, Marta; Alessia, Aragona; Tranquilli, Daniela; Aragona, Cesare. - In: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. - ISSN 1046-7408. - STAMPA. - 70:4(2013), pp. 336-341. [10.1111/aji.12113]

Thyroid Function in Infertile Patients Undergoing Assisted Reproduction

FUMAROLA, Angela;GRANI, Giorgio;ROMANZI, DANIELA;DEL SORDO, MARIANNA;BIANCHINI, MARTA;TRANQUILLI, Daniela;ARAGONA, Cesare
2013

Abstract

Thyroid disease is one of the most common endocrine conditions affecting women during reproductive age. A link between thyroid and assisted reproduction outcome is debated. Serum TSH levels, number and scoring of oocytes and embryos, and number of clinical pregnancies were retrospectively recorded in 164 women undergoing assisted reproduction technologies (ART) at an University-based fertility center, to evaluate the outcome of the first steps of assisted reproduction (ovarian stimulation, oocyte pickup and fertilization, embryo transfer and implantation) in relation to thyroid function and autoimmunity. No significant relationship was found between TSH and all parameters, except clinical pregnancy rate (22.3% in TSH ≤ 2.5 group versus 8.9% in TSH > 2.5 mUI/L group; P = 0.045). No pregnancy occurred in women with anti-thyroperoxidase autoantibodies, while pregnancy occurred in 23.9% of cycles without autoimmunity (P = 0.02). Further studies must be conducted in order to shed light on the link between infertility and thyroid dysfunction. © 2013 John Wiley & Sons Ltd.
2013
icsi; embryos; thyroid; thyrotropin; oocytes
01 Pubblicazione su rivista::01a Articolo in rivista
Thyroid Function in Infertile Patients Undergoing Assisted Reproduction / Fumarola, Angela; Grani, Giorgio; Romanzi, Daniela; DEL SORDO, Marianna; Bianchini, Marta; Alessia, Aragona; Tranquilli, Daniela; Aragona, Cesare. - In: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. - ISSN 1046-7408. - STAMPA. - 70:4(2013), pp. 336-341. [10.1111/aji.12113]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/513366
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