t has been reported that the occurrence of sequences of consecutive beats characterized by SAP and PI changing in the opposite direction (nonbaroreflex sequences) might represent the expression of neural cardiovascular regulatory mechanisms operating with feedforward characteristics. However, these results have been obtained in anesthetized animal models. Due to the widely reported influence of anesthetic agents on the autonomic nervous system the aim of the present study was to test the physiological meaning of nonbaroreflex sequences in conscious, unrestricted and freely moving rats. We studied conscious rats before and ; 3) parasympathetic blockade. Our results confirm and reinforce the physiological role of the “nonbaroreflex” sequences as expression of an integrated, neurallymediated, feedforward type of short-term cardiovascular regulation able to interact dynamically with the feedback mechanisms of baroreflex origin in the control of heart period.
Feedforward neural regulation of circulation in conscious rats / S., Sacco; J. M., Legramante; R., Fiaccavento; P., Di Nardo; Raimondi, Gianfranco; M., Pallante; A., Galante. - In: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. - ISSN 0022-2828. - STAMPA. - 42:(2007), pp. 102-103.
Feedforward neural regulation of circulation in conscious rats
RAIMONDI, GIANFRANCO;
2007
Abstract
t has been reported that the occurrence of sequences of consecutive beats characterized by SAP and PI changing in the opposite direction (nonbaroreflex sequences) might represent the expression of neural cardiovascular regulatory mechanisms operating with feedforward characteristics. However, these results have been obtained in anesthetized animal models. Due to the widely reported influence of anesthetic agents on the autonomic nervous system the aim of the present study was to test the physiological meaning of nonbaroreflex sequences in conscious, unrestricted and freely moving rats. We studied conscious rats before and ; 3) parasympathetic blockade. Our results confirm and reinforce the physiological role of the “nonbaroreflex” sequences as expression of an integrated, neurallymediated, feedforward type of short-term cardiovascular regulation able to interact dynamically with the feedback mechanisms of baroreflex origin in the control of heart period.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
