In this paper we re-examine the commonly accepted meaning of the two kinetic constants characterizing any enzymatic reaction, according to Michaelis-Menten kinetics. Expanding in terms of exponentials the solutions of the ODEs governing the reaction, we determine a new constant, which corrects some misinterpretations of current biochemical literature.
Is there still something to say on enzyme kinetic constants and quasi-steady state approximation? / Bersani, Alberto Maria; Dell'Acqua, Guido. - ELETTRONICO. - 1:(2010), pp. 204-215. (Intervento presentato al convegno 10th International Conference on Computational and Mathematical Methods in Science and Engineering, CMMSE 2010 tenutosi a Almería (Andalucía), Spain nel June 26-30 2010).
Is there still something to say on enzyme kinetic constants and quasi-steady state approximation?
BERSANI, Alberto Maria;DELL'ACQUA, Guido
2010
Abstract
In this paper we re-examine the commonly accepted meaning of the two kinetic constants characterizing any enzymatic reaction, according to Michaelis-Menten kinetics. Expanding in terms of exponentials the solutions of the ODEs governing the reaction, we determine a new constant, which corrects some misinterpretations of current biochemical literature.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
