Intravascular catheters are widely employed in healthcare settings. Howevere, local or system infections are frequently associated to their use. In this study we experimented a novel approach to prevent medical device-related infections based on the adsorption of antibiotics onto functionalized polyurethanes. The best polymer-antibiotic system developed by us consisted of a basic polyurethane loaded with rifampin, whose antibacterial activity lasted up to 8 months.
In vitro experimental model to prevent microbial colonization of intravascular catheters and related infections / Francolini, Iolanda; DI ROSA, Roberta; Piozzi, Antonella; Marconi, Valter; G., Donelli. - STAMPA. - (2003), pp. 15-15. (Intervento presentato al convegno 4th International Symposium Perspectives in Clinical Microbiology and Infections tenutosi a Venice, Italy nel January 12-15).
In vitro experimental model to prevent microbial colonization of intravascular catheters and related infections
FRANCOLINI, IOLANDA;DI ROSA, Roberta;PIOZZI, Antonella;MARCONI, Valter;
2003
Abstract
Intravascular catheters are widely employed in healthcare settings. Howevere, local or system infections are frequently associated to their use. In this study we experimented a novel approach to prevent medical device-related infections based on the adsorption of antibiotics onto functionalized polyurethanes. The best polymer-antibiotic system developed by us consisted of a basic polyurethane loaded with rifampin, whose antibacterial activity lasted up to 8 months.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
