Some results and some general observations on the reactivity of different substrates in lipase-catalyzed reactions in supercritical carbon dioxide are reported. Chiral 1 -phenylethanol, 2-octanol, 6-methyl-5-hepten-2-ol and trans-3-penten-2-ol have been prepared in high enantiomeric excess (ee > 80%) by enantioselective acetylation of the corresponding racemic alcohols using immobilized crude lipase (Pseudomonas sp. from Amano) in supercritical carbon dioxide.
Enantioselectivity and reactivity of immobilized lipase in supercritical carbon dioxide / Cernia, Enrico; Palocci, Cleofe; Gasparrini, Francesco; Misiti, Domenico; N., Fagnano. - In: JOURNAL OF MOLECULAR CATALYSIS. - ISSN 0304-5102. - STAMPA. - 89:(1994), pp. 11-18. [10.1016/0304-5102(93)E0289-S]
Enantioselectivity and reactivity of immobilized lipase in supercritical carbon dioxide
CERNIA, Enrico;PALOCCI, Cleofe;GASPARRINI, Francesco;MISITI, Domenico;
1994
Abstract
Some results and some general observations on the reactivity of different substrates in lipase-catalyzed reactions in supercritical carbon dioxide are reported. Chiral 1 -phenylethanol, 2-octanol, 6-methyl-5-hepten-2-ol and trans-3-penten-2-ol have been prepared in high enantiomeric excess (ee > 80%) by enantioselective acetylation of the corresponding racemic alcohols using immobilized crude lipase (Pseudomonas sp. from Amano) in supercritical carbon dioxide.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
