To analyze the modifications in serum PSA levels during IAD in patients with an initial PSA progression after radical retropubic prostatectomy (RRP). Between February 1994 and May 1996, 34 consecutive patients with an initial PSA progression (> 0.4 ng/ml) after RRP were selected. All men had localized adenocarcinoma of the prostate, stage pT2 pN0 M0. Patients were offered IAD when PSA progressed over 0.4 ng/ml. The initial treatment period with complete androgen deprivation (CAD lasted 24 weeks in all cases. After, an acceptable nadir PSA level was considered to be a value less than or equal to 0.4 ng/ml. CAD was then withheld until serum PSA increased to a value over 0.4 ng/ml. Follow-up ranges from 144 to 228 weeks. We suggest that IAD may be an effective therapy in patients with an initial PSA progression after RRP.

Serum prostate specific antigen (PSA) levels during intermittent androgen deprivation (IAD) in patients with PSA progression after radical prostatectomy / Sciarra, Alessandro; D'Eramo, Giuseppe; S., Di Nicola; Casale, Paolo; A., Loreto; D., Colella; G., Voria; DI SILVERIO, Franco. - STAMPA. - (1999), pp. 141-144. (Intervento presentato al convegno 6th Congress of the Mediterranean-Urological-Association tenutosi a CAIRO, EGYPT nel SEP 06-09, 1999).

Serum prostate specific antigen (PSA) levels during intermittent androgen deprivation (IAD) in patients with PSA progression after radical prostatectomy

SCIARRA, Alessandro;D'ERAMO, Giuseppe;CASALE, PAOLO;DI SILVERIO, Franco
1999

Abstract

To analyze the modifications in serum PSA levels during IAD in patients with an initial PSA progression after radical retropubic prostatectomy (RRP). Between February 1994 and May 1996, 34 consecutive patients with an initial PSA progression (> 0.4 ng/ml) after RRP were selected. All men had localized adenocarcinoma of the prostate, stage pT2 pN0 M0. Patients were offered IAD when PSA progressed over 0.4 ng/ml. The initial treatment period with complete androgen deprivation (CAD lasted 24 weeks in all cases. After, an acceptable nadir PSA level was considered to be a value less than or equal to 0.4 ng/ml. CAD was then withheld until serum PSA increased to a value over 0.4 ng/ml. Follow-up ranges from 144 to 228 weeks. We suggest that IAD may be an effective therapy in patients with an initial PSA progression after RRP.
1999
6th Congress of the Mediterranean-Urological-Association
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
Serum prostate specific antigen (PSA) levels during intermittent androgen deprivation (IAD) in patients with PSA progression after radical prostatectomy / Sciarra, Alessandro; D'Eramo, Giuseppe; S., Di Nicola; Casale, Paolo; A., Loreto; D., Colella; G., Voria; DI SILVERIO, Franco. - STAMPA. - (1999), pp. 141-144. (Intervento presentato al convegno 6th Congress of the Mediterranean-Urological-Association tenutosi a CAIRO, EGYPT nel SEP 06-09, 1999).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/502954
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