This paper describes the inhibitory effect of a normal rat brain solubilized membrane preparation (RBSM-liposomes) on rabies virus infection. Rabies virus was incubated with RBSM-liposomes or their separated components (proteins, phospholipids, gangliosides) before infection of CER or neuroblastoma cells. In addition, both RBSM-liposomes and target cells were treated with enzymes prior to the infection step. All these experimental procedures showed that the active components were mainly lipids.
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|Titolo:||inhibition of rabies virus infection by a soluble membrane fraction from the rat cemtral nervous system|
|Data di pubblicazione:||1988|
|Appartiene alla tipologia:||01a Articolo in rivista|