This paper describes the inhibitory effect of a normal rat brain solubilized membrane preparation (RBSM-liposomes) on rabies virus infection. Rabies virus was incubated with RBSM-liposomes or their separated components (proteins, phospholipids, gangliosides) before infection of CER or neuroblastoma cells. In addition, both RBSM-liposomes and target cells were treated with enzymes prior to the infection step. All these experimental procedures showed that the active components were mainly lipids.
inhibition of rabies virus infection by a soluble membrane fraction from the rat cemtral nervous system / Conti, Cinzia; Hauttecoeur, B.; Morelec, m. j.; Bizzini, B.; Orsi, Nicola; Tsiang, H.. - In: ARCHIVES OF VIROLOGY. - ISSN 0304-8608. - STAMPA. - 98:(1988), pp. 73-86.
inhibition of rabies virus infection by a soluble membrane fraction from the rat cemtral nervous system
CONTI, Cinzia;ORSI, Nicola;
1988
Abstract
This paper describes the inhibitory effect of a normal rat brain solubilized membrane preparation (RBSM-liposomes) on rabies virus infection. Rabies virus was incubated with RBSM-liposomes or their separated components (proteins, phospholipids, gangliosides) before infection of CER or neuroblastoma cells. In addition, both RBSM-liposomes and target cells were treated with enzymes prior to the infection step. All these experimental procedures showed that the active components were mainly lipids.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
