The Deep Brain Stimulation is a technique consisting in the electrical stimulation of basal ganglia, through pulsed signals (repetition frequencies ≈ 100 Hz), delivered by implanted electrodes. It is efficiently used in the treatment of movement disorders, especially Parkinson's disease, but the underlying mechanisms of action are still unknown. To understand these mechanisms an accurate dosimetric evaluation is unavoidable. Therefore, we developed a 3-D electromagnetic model of the anatomic structures affected by stimulation, the surrounding conducting volume, and the stimulating conditions. The model was used to predict the effect of the stimulation on neuronal fibres.
A 3-D Model for Dosimetric Studies on Deep Brain Stimulation / Fernando, Maggio; Liberti, Micaela; Apollonio, Francesca; Marta, Parazzini; Paolo, Ravazzani; D'Inzeo, Guglielmo; Paffi, Alessandra. - ELETTRONICO. - (2011). (Intervento presentato al convegno 10th International Congress of the European Bioelectromagnetics Association tenutosi a Roma nel February 21-24).
A 3-D Model for Dosimetric Studies on Deep Brain Stimulation
LIBERTI, Micaela;APOLLONIO, Francesca;D'INZEO, Guglielmo;PAFFI, ALESSANDRA
2011
Abstract
The Deep Brain Stimulation is a technique consisting in the electrical stimulation of basal ganglia, through pulsed signals (repetition frequencies ≈ 100 Hz), delivered by implanted electrodes. It is efficiently used in the treatment of movement disorders, especially Parkinson's disease, but the underlying mechanisms of action are still unknown. To understand these mechanisms an accurate dosimetric evaluation is unavoidable. Therefore, we developed a 3-D electromagnetic model of the anatomic structures affected by stimulation, the surrounding conducting volume, and the stimulating conditions. The model was used to predict the effect of the stimulation on neuronal fibres.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
