Comparazione dell’efficacia di differenti antibiotici sistemici nel trattamento dell’acne intermedia

SUMMARY: Comparison of the efficacy of different systemic antibiotics in the treatment of intermediate acne. E. PAPUZZO, G. LUCCIOLA, E. TOLINO, F. NICOLUCCI, N. SKROZA, B. GROSSI, D. INNOCENZI Aim of our study is to evaluate the modifications of the clinical aspect and of the quality of life in 115 patients (64 male, 51 females, 19 years average age) affected by intermediate acne treated with four different antibiotics (lymecycline, doxycycline, methacycline, azythromycin). Our study clearly showed that azythromycin, doxycycline, lymecycline and methacycline are effective in the treatment of the acne, considerably improving the clinical aspect of the patients and the quality of life. There were not significant differences concerning sex. Regarding quality of life, female subjects showed, at the end of the therapy, a more evident improvement compared with male patients. The subjects between 25 and the 39 years presented, at the end of the treatment, a remarkable improvement of the clinical aspect compared with patient of different age. In conclusion systemic antibiotics therapy determinates improvement of the clinical aspect and of the quality of life in patients with intermediate acne. Such improvement is not related to sex. Subjects aged between 25 and the 39 years have a most important improvement compared with patients of different age.