An experimental study on rats in order to discovery any possible interaction between Ciclosporin (CyA) and H2-receptor antagonists has been carried out. The results obtained demonstrated that the serum levels of CyA were higher in rats treated with CyA and Cimetidine or Ranitidine, but not Famotidine. It is probable that the increase of ciclosporinaemia is the consequence of an increased hepatotoxicity due to administration of Cya in association with Cimetidine or Ranitidine.

[Cyclosporin (CyA) and H2 antagonists] / V., Filingeri; R., Rosati; A., Iacona; R., Giacomelli; G., Famularo; Calogero, Antonella; V., Cervelli; G., Tonietti; C. U., Casciani. - In: MINERVA MEDICA. - ISSN 0026-4806. - STAMPA. - 81:5(1990), pp. 399-402.

[Cyclosporin (CyA) and H2 antagonists].

CALOGERO, ANTONELLA;
1990

Abstract

An experimental study on rats in order to discovery any possible interaction between Ciclosporin (CyA) and H2-receptor antagonists has been carried out. The results obtained demonstrated that the serum levels of CyA were higher in rats treated with CyA and Cimetidine or Ranitidine, but not Famotidine. It is probable that the increase of ciclosporinaemia is the consequence of an increased hepatotoxicity due to administration of Cya in association with Cimetidine or Ranitidine.
1990
01 Pubblicazione su rivista::01a Articolo in rivista
[Cyclosporin (CyA) and H2 antagonists] / V., Filingeri; R., Rosati; A., Iacona; R., Giacomelli; G., Famularo; Calogero, Antonella; V., Cervelli; G., Tonietti; C. U., Casciani. - In: MINERVA MEDICA. - ISSN 0026-4806. - STAMPA. - 81:5(1990), pp. 399-402.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/500502
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