A 38-year-old woman is described to have a primary hyperaldosteronism due to an aldosteronoma with foci of lymphocytic infiltration. The finding suggests: a concomitant lymphoid adrenalitis; or, an immunological attack to neoplastic cells. The hypothesis is that there may be a relationship in the association. The lymphocytic infiltrates could have a pathogenic role in the development of the aldosterone-producing adrenocortical neoplasm by interrupting some inhibitory mechanism(s) of the cells that secrete aldosterone.
May a lymphocytic infiltration have a pathogenic role in an aldosterone-producing adrenal tumor? / Cugini, Pietro; Lucia, Piernatale; Letizia, Claudio; G., Murano; S., Pieche. - In: MEDICAL HYPOTHESES. - ISSN 0306-9877. - 17:1(1985), pp. 33-38.
May a lymphocytic infiltration have a pathogenic role in an aldosterone-producing adrenal tumor?
CUGINI, Pietro;LUCIA, Piernatale;LETIZIA, Claudio;
1985
Abstract
A 38-year-old woman is described to have a primary hyperaldosteronism due to an aldosteronoma with foci of lymphocytic infiltration. The finding suggests: a concomitant lymphoid adrenalitis; or, an immunological attack to neoplastic cells. The hypothesis is that there may be a relationship in the association. The lymphocytic infiltrates could have a pathogenic role in the development of the aldosterone-producing adrenocortical neoplasm by interrupting some inhibitory mechanism(s) of the cells that secrete aldosterone.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
