Aim: To investigate the effects of adherence to the Mediterranean diet and familial dysmetabolisms on acne development. Methods: A community-based case-control study was carried out in Italy enrolling cases as acneic outpatients of a dermatological ambulatory service and controls as clinically healthy acne-free subjects. Food consumption were evaluated with a validated food-frequency questionnaire, exploring the consumption of pasta, meat, cheese, fish, fruit, vegetables, and olive oil. Adherence to the traditional Mediterranean diet was assessed by a 10-point Mediterranean diet scale that incorporated the main characteristics of this diet. A logistic regression analysis estimated the variables who predicted the odds of being case, using those variables that at the univariate analysis yielded a p-value < 0.25. Results are presented as odds ratio (OR) or adjusted OR (AOR). Results: The study included 93 cases (36.6% males, median age 17 years) and 200 controls (32% males, median age 16 years). The Mediterranean diet score >= 6 revealed a protective effect towards acne (crude OR 0.22, 95% CI 0.08-0.64). Logistic regression analysis showed that familial hypercholesterolaemia, diabetes, and hypertension are strong risk factors for acne (AOR 8.79, 95% CI 1.67-46.22; 3.32, 95% CI 1.27-8.63; and 2.73, 95% CI 1.07-6.96, respectively), while the Mediterranean diet represents a protective factor (score >= 6, AOR 0.31, 95% CI 0.11-0.89). Conclusions: The odds for familial dysmetabolisms was higher in cases than in controls, confirming their role in determining or maintaining acne. Moreover, this is the first study demonstrating a protective role of the Mediterranean diet in the pathogenesis of acne.

Mediterranean diet and familial dysmetabolism as factors influencing the development of acne / Skroza, Nevena; Tolino, Ersilia; Semyonov, Leda; Proietti, Ilaria; Bernardini, Nicoletta; Nicolucci, Francesca; LA VIOLA, Giorgio; Giuseppe, Prete; Saulle, Rosella; Potenza, Concetta; LA TORRE, Giuseppe. - In: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. - ISSN 1403-4948. - 40:5(2012), pp. 466-474. [10.1177/1403494812454235]

Mediterranean diet and familial dysmetabolism as factors influencing the development of acne

SKROZA, Nevena;TOLINO, ERSILIA;SEMYONOV, LEDA;PROIETTI, ILARIA;BERNARDINI, NICOLETTA;NICOLUCCI, FRANCESCA;LA VIOLA, GIORGIO;Rosella Saulle;POTENZA, Concetta;LA TORRE, Giuseppe
2012

Abstract

Aim: To investigate the effects of adherence to the Mediterranean diet and familial dysmetabolisms on acne development. Methods: A community-based case-control study was carried out in Italy enrolling cases as acneic outpatients of a dermatological ambulatory service and controls as clinically healthy acne-free subjects. Food consumption were evaluated with a validated food-frequency questionnaire, exploring the consumption of pasta, meat, cheese, fish, fruit, vegetables, and olive oil. Adherence to the traditional Mediterranean diet was assessed by a 10-point Mediterranean diet scale that incorporated the main characteristics of this diet. A logistic regression analysis estimated the variables who predicted the odds of being case, using those variables that at the univariate analysis yielded a p-value < 0.25. Results are presented as odds ratio (OR) or adjusted OR (AOR). Results: The study included 93 cases (36.6% males, median age 17 years) and 200 controls (32% males, median age 16 years). The Mediterranean diet score >= 6 revealed a protective effect towards acne (crude OR 0.22, 95% CI 0.08-0.64). Logistic regression analysis showed that familial hypercholesterolaemia, diabetes, and hypertension are strong risk factors for acne (AOR 8.79, 95% CI 1.67-46.22; 3.32, 95% CI 1.27-8.63; and 2.73, 95% CI 1.07-6.96, respectively), while the Mediterranean diet represents a protective factor (score >= 6, AOR 0.31, 95% CI 0.11-0.89). Conclusions: The odds for familial dysmetabolisms was higher in cases than in controls, confirming their role in determining or maintaining acne. Moreover, this is the first study demonstrating a protective role of the Mediterranean diet in the pathogenesis of acne.
2012
acne; case-control study; dysmetabolism; familiarity; mediterranean diet; nutrition
01 Pubblicazione su rivista::01a Articolo in rivista
Mediterranean diet and familial dysmetabolism as factors influencing the development of acne / Skroza, Nevena; Tolino, Ersilia; Semyonov, Leda; Proietti, Ilaria; Bernardini, Nicoletta; Nicolucci, Francesca; LA VIOLA, Giorgio; Giuseppe, Prete; Saulle, Rosella; Potenza, Concetta; LA TORRE, Giuseppe. - In: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. - ISSN 1403-4948. - 40:5(2012), pp. 466-474. [10.1177/1403494812454235]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/492275
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