A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.

Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus / Frustaci, Andrea; N., Gentiloni; M., Caldarulo. - In: CHEST. - ISSN 0012-3692. - STAMPA. - 109:1(1996), pp. 282-284.

Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus.

FRUSTACI, ANDREA;
1996

Abstract

A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported. A diagnosis of SLE was suspected owing to the presence of active lymphocytic myocarditis and fibrinous endocarditis at LV endomyocardial biopsy and was confirmed by identification of 4 of the 11 criteria proposed by the American Rheumatism Association for the definition of SLE. A 2-month period of steroid therapy was followed by a remarkable recovery of LV function and progression of endomyocarditis to a healed phase at control LV biopsy. The LV aneurysm disappeared, likely because thrombosis occurred as a result of the hypercoagulable state accompanying the presence of anticardiolipin antibodies. This is the first reported case of LV aneurysm induced by SLE and is a rare clinicohistologic documentation of the effectiveness of steroid treatment on lupus endomyocarditis.
1996
01 Pubblicazione su rivista::01a Articolo in rivista
Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus / Frustaci, Andrea; N., Gentiloni; M., Caldarulo. - In: CHEST. - ISSN 0012-3692. - STAMPA. - 109:1(1996), pp. 282-284.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/490816
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