The condensation of calf thymus DNA into the cholesteric-like Psi-phase was observed by circular dichroism in liposome suspensions formulated with specific cationic gemini surfactants. The stereochemistry of the gemini spacer, the presence of specific functional groups, and the covalent link between the headgroups are fundamental issues in the condensation of DNA. Transmission electron microscopy images showed a multilamellar morphology, which corresponds with condensation.

Role of the Spacer of cationic gemini amphiphiles in the condensation of DNA / Cecilia, Bombelli; Stefano, Borocci; Marco, Diociaiuti; F., Faggioli; Galantini, Luciano; Paola, Luciani; Giovanna, Mancini; Maria Grazia, Sacco. - In: LANGMUIR. - ISSN 0743-7463. - 21:23(2005), pp. 10271-10274. [10.1021/la051324+]

Role of the Spacer of cationic gemini amphiphiles in the condensation of DNA

GALANTINI, Luciano;
2005

Abstract

The condensation of calf thymus DNA into the cholesteric-like Psi-phase was observed by circular dichroism in liposome suspensions formulated with specific cationic gemini surfactants. The stereochemistry of the gemini spacer, the presence of specific functional groups, and the covalent link between the headgroups are fundamental issues in the condensation of DNA. Transmission electron microscopy images showed a multilamellar morphology, which corresponds with condensation.
2005
01 Pubblicazione su rivista::01a Articolo in rivista
Role of the Spacer of cationic gemini amphiphiles in the condensation of DNA / Cecilia, Bombelli; Stefano, Borocci; Marco, Diociaiuti; F., Faggioli; Galantini, Luciano; Paola, Luciani; Giovanna, Mancini; Maria Grazia, Sacco. - In: LANGMUIR. - ISSN 0743-7463. - 21:23(2005), pp. 10271-10274. [10.1021/la051324+]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/48939
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