Three new pyrrolidinium based surfactants were synthesized and characterized as pure aggregate components and in mixtures with 1,2-dimyristoyl- sn-glycero-3-phosphocholine to understand how the molecular structure of the cationic amphiphile and its mole percentage might affect the physicochemical properties of the resulting aggregates. The thermotropic behavior of the mixed liposomes was investigated by differential scanning calorimetry on multilamellar vesicles, whereas their size and surface potential were investigated on large unilamellar vesicles by dynamic laser light scattering and fluorescence experiments, respectively. The presence of either methoxy or hydroxy groups in the positions 3 and 4 of the pyrrolidinium ring as well as the presence of a second alkyl chain on pyrrolidinium nitrogen, controls the aggregates features. © 2012 Elsevier Inc.
Synthesis and physicochemical characterization of pyrrolidinium based surfactants / Bartoloni, Alessandra; Bombelli, Cecilia; Borocci, Stefano; Bonicelli, Maria Grazia; Galantini, Luciano; Giansanti, Luisa; Marco, Ierino; Giovanna, Mancini; Alessandra, Muschietti; Claudio, Sperduto. - In: JOURNAL OF COLLOID AND INTERFACE SCIENCE. - ISSN 0021-9797. - STAMPA. - 392:1(2013), pp. 297-303. [10.1016/j.jcis.2012.09.065]
Synthesis and physicochemical characterization of pyrrolidinium based surfactants
BARTOLONI, ALESSANDRA;BOMBELLI, Cecilia;BOROCCI, Stefano;BONICELLI, Maria Grazia;GALANTINI, Luciano;GIANSANTI, LUISA;
2013
Abstract
Three new pyrrolidinium based surfactants were synthesized and characterized as pure aggregate components and in mixtures with 1,2-dimyristoyl- sn-glycero-3-phosphocholine to understand how the molecular structure of the cationic amphiphile and its mole percentage might affect the physicochemical properties of the resulting aggregates. The thermotropic behavior of the mixed liposomes was investigated by differential scanning calorimetry on multilamellar vesicles, whereas their size and surface potential were investigated on large unilamellar vesicles by dynamic laser light scattering and fluorescence experiments, respectively. The presence of either methoxy or hydroxy groups in the positions 3 and 4 of the pyrrolidinium ring as well as the presence of a second alkyl chain on pyrrolidinium nitrogen, controls the aggregates features. © 2012 Elsevier Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
