Maternal age significantly aff ects the outcome of ART by lowering oocyte quality and competence. However, the morphological ultrastructure features of aged human oocytes have been not extensively studied and understood. In this study we analyzed oocytes donated by women <35 (-35) and ? 35 (+35) years old, enrolled in an IVF program, after informed consent. MII oocytes, fi xed at time of pick up (in vivo) or after 24 hours culture (in vitro) were evaluated by light and transmission electron microscopy.
Morphological aspects of human aged oocytes: an in vivo and in vitro ultrastructural study / Bianchi, S; Maione, M; Lorenzo, C; Micara, Giulietta; Linari, Antonella; Tranquilli, Daniela; Aragona, Cesare; Macchiarelli, G; Nottola, Stefania Annarita. - In: ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY. - ISSN 2038-5129. - STAMPA. - 116, N. 1 (suppl):(2011), pp. 25----. (Intervento presentato al convegno 65° Congresso Nazionale della Società Italiana di Anatomia e Istologia tenutosi a Padova nel 27-29 Settembre 2011).
Morphological aspects of human aged oocytes: an in vivo and in vitro ultrastructural study
MICARA, Giulietta;LINARI, Antonella;TRANQUILLI, Daniela;ARAGONA, Cesare;NOTTOLA, Stefania Annarita
2011
Abstract
Maternal age significantly aff ects the outcome of ART by lowering oocyte quality and competence. However, the morphological ultrastructure features of aged human oocytes have been not extensively studied and understood. In this study we analyzed oocytes donated by women <35 (-35) and ? 35 (+35) years old, enrolled in an IVF program, after informed consent. MII oocytes, fi xed at time of pick up (in vivo) or after 24 hours culture (in vitro) were evaluated by light and transmission electron microscopy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
