The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function. © 2012 Published by Elsevier Inc.
Stages of Early Acute Renal Dysfunction in Liver Transplantation: The Influence of Graft Function / Umbro, Ilaria; Rossi, Massimo; Tinti, Francesca; F., Fiacco; P., Piselli; S., Ianni; GINANNI CORRADINI, Stefano; Poli, Luca; Berloco, Pasquale Bartolomeo; Mitterhofer, Anna Paola. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - STAMPA. - 44:7(2012), pp. 1953-1955. (Intervento presentato al convegno 35th Annual Congress of the Italian-Society-of-Organ-Transplantation (SITO) tenutosi a Rome, ITALY nel OCT 27-29, 2011) [10.1016/j.transproceed.2012.06.020].
Stages of Early Acute Renal Dysfunction in Liver Transplantation: The Influence of Graft Function
UMBRO, ILARIA;ROSSI, MASSIMO;TINTI, FRANCESCA;GINANNI CORRADINI, Stefano;POLI, Luca;BERLOCO, Pasquale Bartolomeo;MITTERHOFER, Anna Paola
2012
Abstract
The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function. © 2012 Published by Elsevier Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.