A rare case of splenic marginal zone lymphoma (SMZL) in a human immunodeficiency virus (HIV)-1 infected patient is described. As an association between SMZL and viral infections has been reported, the presence of the hepatitis C virus and HIV-1 genomes was evaluated. Only HIV-1 DNA levels were detected in enriched splenic B lymphocytes, suggesting a HIV-1 involvement in lymphomagenesis.
Splenic marginal zone lymphoma in a HIV-1 infected patient: evidence favouring a pathogenetic role of HIV-1 itself in the lymphomagenesis / Cagliuso, Maria; Conti, Valentina; Stefania, Trasarti; Lombardi, Laura; Riminucci, Mara; Perez, Marie; Turriziani, Ombretta; Falasca, Francesca; Mauro, Nanni; Tafuri, Agostino; Mezzaroma, Ivano. - In: INFECTION. - ISSN 0300-8126. - STAMPA. - 41:1(2013), pp. 255-258. [10.1007/s15010-012-0344-4]
Splenic marginal zone lymphoma in a HIV-1 infected patient: evidence favouring a pathogenetic role of HIV-1 itself in the lymphomagenesis
CAGLIUSO, MARIA;CONTI, VALENTINA;LOMBARDI, LAURA;RIMINUCCI, MARA;TURRIZIANI, Ombretta;FALASCA, FRANCESCA;TAFURI, Agostino;MEZZAROMA, Ivano
2013
Abstract
A rare case of splenic marginal zone lymphoma (SMZL) in a human immunodeficiency virus (HIV)-1 infected patient is described. As an association between SMZL and viral infections has been reported, the presence of the hepatitis C virus and HIV-1 genomes was evaluated. Only HIV-1 DNA levels were detected in enriched splenic B lymphocytes, suggesting a HIV-1 involvement in lymphomagenesis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
