The use of β-enaminones in synthesis is a subject of great current interest, mostly because of their electronic properties. An appropriate design of the starting β-enaminone could allow for obtaining several classes of heterocyclic derivs. through base- or transition metal-catalyzed reactions. E.g., preparation. of a β-enaminone by reaction of 2-BrC6H4COC≡CPh, followed by addittion of CuI, K2CO3, and DMEDA in DMSO, gave 88% 4-quinolone derivative (I).
Copper-catalyzed synthesis of heterocycle derivatives: use of β-enaminones / Cacchi, Sandro; Fabrizi, Giancarlo; Goggiamani, Antonella. - In: LA CHIMICA E L'INDUSTRIA. - ISSN 0009-4315. - STAMPA. - 94:(2012), pp. 69-73.
Copper-catalyzed synthesis of heterocycle derivatives: use of β-enaminones
CACCHI, Sandro;FABRIZI, Giancarlo;GOGGIAMANI, ANTONELLA
2012
Abstract
The use of β-enaminones in synthesis is a subject of great current interest, mostly because of their electronic properties. An appropriate design of the starting β-enaminone could allow for obtaining several classes of heterocyclic derivs. through base- or transition metal-catalyzed reactions. E.g., preparation. of a β-enaminone by reaction of 2-BrC6H4COC≡CPh, followed by addittion of CuI, K2CO3, and DMEDA in DMSO, gave 88% 4-quinolone derivative (I).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
