Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells. Much evidence suggests that, beyond their involvement in neuroinflammation, these proteins play a role in neurodevelopment and neurophysiological signaling. The goal of this review is to summarize recent information concerning expression, signaling, and function of CXC chemokine receptor in the CNS, with the main focus on the developmental and neuromodulatory actions of chemokines in the cerebellum.

CXC chemokine receptors in the central nervous system: Role in cerebellar neuromodulation and development / Ragozzino, Davide Antonio. - In: JOURNAL OF NEUROVIROLOGY. - ISSN 1355-0284. - 8:6(2002), pp. 559-572. [10.1080/13550280290100932]

CXC chemokine receptors in the central nervous system: Role in cerebellar neuromodulation and development

RAGOZZINO, Davide Antonio
2002

Abstract

Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells. Much evidence suggests that, beyond their involvement in neuroinflammation, these proteins play a role in neurodevelopment and neurophysiological signaling. The goal of this review is to summarize recent information concerning expression, signaling, and function of CXC chemokine receptor in the CNS, with the main focus on the developmental and neuromodulatory actions of chemokines in the cerebellum.
2002
cerebellum; cxc chemokine; development; neutrotransmission
01 Pubblicazione su rivista::01a Articolo in rivista
CXC chemokine receptors in the central nervous system: Role in cerebellar neuromodulation and development / Ragozzino, Davide Antonio. - In: JOURNAL OF NEUROVIROLOGY. - ISSN 1355-0284. - 8:6(2002), pp. 559-572. [10.1080/13550280290100932]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/48113
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