Thrombocytopenia is a rare complication of glycoprotein IIb/IIIa treatment. We report a case of an acute profound abciximab induced thrombocytopenia and its successful management. The patient, presenting with unstable angina, underwent percutaneous coronary intervention with implantation of three drug eluting stents without receiving a clopidogrel loading dose according to guidelines. The rapid drop in the platelet count after abciximab elastomeric pump infusion was treated with drug discontinuation and platelet transfusion. The high risk of stent thrombosis was avoided by a timely readministration of the dual antiplatelet treatment.

Acute profound abciximab induced thrombocytopenia: a correct management of a methodological error / Tanzilli, Gaetano; M., Sordi; A., Arrivi; Mangieri, Enrico; M., Scappaticci. - In: BMJ. BRITISH MEDICAL JOURNAL. - ISSN 0959-8138. - ELETTRONICO. - (2009), pp. .......-........ [10.1136/bcr.12.2008.1381]

Acute profound abciximab induced thrombocytopenia: a correct management of a methodological error

TANZILLI, Gaetano;MANGIERI, Enrico;
2009

Abstract

Thrombocytopenia is a rare complication of glycoprotein IIb/IIIa treatment. We report a case of an acute profound abciximab induced thrombocytopenia and its successful management. The patient, presenting with unstable angina, underwent percutaneous coronary intervention with implantation of three drug eluting stents without receiving a clopidogrel loading dose according to guidelines. The rapid drop in the platelet count after abciximab elastomeric pump infusion was treated with drug discontinuation and platelet transfusion. The high risk of stent thrombosis was avoided by a timely readministration of the dual antiplatelet treatment.
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Acute profound abciximab induced thrombocytopenia: a correct management of a methodological error / Tanzilli, Gaetano; M., Sordi; A., Arrivi; Mangieri, Enrico; M., Scappaticci. - In: BMJ. BRITISH MEDICAL JOURNAL. - ISSN 0959-8138. - ELETTRONICO. - (2009), pp. .......-........ [10.1136/bcr.12.2008.1381]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/476329
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