The C1q-binding assay was performed on 30 sera from patients with Behcet's syndrome and circulating immune complexes were found in 46%. Circulating immune complexes were isolated and purified from the sera of two patients by immunoadsorption on a column of polymethylmetacrylate beads coated with C1q and then labelled with 125I. In double immunodiffusion these purified immune complexes were found to contain IgG, C1q, C1s and C3. Anti-IgG activity was not detectable in the purified immune complexes while specific cross-reactivity was found in a solid-phase radioimmunoassay with the majority of the sera of Behcet's syndrome.
Circulating immune complexes in Behçet's syndrome: purification, characterization and cross-reactivity studies / Valesini, Guido; M., Picardo; R., Pastore; P., Pivetti; U., Serafini. - In: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. - ISSN 0009-9104. - STAMPA. - 44:3(1981), pp. 522-527.
Circulating immune complexes in Behçet's syndrome: purification, characterization and cross-reactivity studies.
VALESINI, Guido;
1981
Abstract
The C1q-binding assay was performed on 30 sera from patients with Behcet's syndrome and circulating immune complexes were found in 46%. Circulating immune complexes were isolated and purified from the sera of two patients by immunoadsorption on a column of polymethylmetacrylate beads coated with C1q and then labelled with 125I. In double immunodiffusion these purified immune complexes were found to contain IgG, C1q, C1s and C3. Anti-IgG activity was not detectable in the purified immune complexes while specific cross-reactivity was found in a solid-phase radioimmunoassay with the majority of the sera of Behcet's syndrome.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
