The ability to estimate the risk of malaria infection is crucial for the development and evaluation of control programmes and currently relies on both entomological and parasitological methods. The availability of rapid and sensitive tools to measure the exposure to Anopheles mosquito bites would be extremely valuable in this context. Human antibody response to Anopheles saliva may represent such an indicator (Remoue F et al, 2006, Trans R Soc Trop Med Hyg). However, mosquito saliva is a complex cocktail of bioactive factors and cross-reactivity with other antigens (i.e. salivary proteins from blood-feeders other than anophelines) may be misleading.
Human IgG response to the Anopheles gambiae salivary protein gSG6: an indicator of exposure to anopheline mosquito bites / Rizzo, Cinzia; R., Ronca; G., Fiorentino; Verra, Federica; Mangano, Valentina; A., Poinsignon; B. S., Sirima; I., Nebie; F., Remoue; COLUZZI BARTOCCIONI, Caio Mario; Petrarca, Vincenzo; Modiano, David; Arca', Bruno. - In: PARASSITOLOGIA. - ISSN 0048-2951. - STAMPA. - 52 (1-2):(2010), pp. 255-255. (Intervento presentato al convegno XXVI Congresso SOCIETA' ITALIANA DI PARASSITOLOGIA tenutosi a Perugia (Italy) nel 22-25 Giugno 2010).
Human IgG response to the Anopheles gambiae salivary protein gSG6: an indicator of exposure to anopheline mosquito bites.
RIZZO, CINZIA;VERRA, FEDERICA;MANGANO, VALENTINA;COLUZZI BARTOCCIONI, Caio Mario;PETRARCA, Vincenzo;MODIANO, David;ARCA', Bruno
2010
Abstract
The ability to estimate the risk of malaria infection is crucial for the development and evaluation of control programmes and currently relies on both entomological and parasitological methods. The availability of rapid and sensitive tools to measure the exposure to Anopheles mosquito bites would be extremely valuable in this context. Human antibody response to Anopheles saliva may represent such an indicator (Remoue F et al, 2006, Trans R Soc Trop Med Hyg). However, mosquito saliva is a complex cocktail of bioactive factors and cross-reactivity with other antigens (i.e. salivary proteins from blood-feeders other than anophelines) may be misleading.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
