The effects of phenylpropanoid glycosides (PhGs) isolated from Calceolaria and Orobanche on platelet aggregation and blood pressure have been investigated. The PhGs tested were able to interfere with platelet aggregation, producing pro- or antiaggregant effects. On the other hand, none of the PhGs tested had a significant effect on blood pressure. The results suggest that the effects of PhGs on rabbit platelets may be related to a differential modulation of cAMP-phosphodiesterase.
PHARMACOLOGICAL STUDY OF PHENYLPROPANOID GLYCOSIDES - PLATELET-AGGREGATION AND BLOOD-PRESSURE STUDIES IN RABBITS AND RATS / A., Capasso; S., Pieretti; A., Di Giannuario; Nicoletti, Marcello. - In: PHYTOTHERAPY RESEARCH. - ISSN 0951-418X. - STAMPA. - 7:1(1993), pp. 81-83. [10.1002/ptr.2650070119]
PHARMACOLOGICAL STUDY OF PHENYLPROPANOID GLYCOSIDES - PLATELET-AGGREGATION AND BLOOD-PRESSURE STUDIES IN RABBITS AND RATS
NICOLETTI, Marcello
1993
Abstract
The effects of phenylpropanoid glycosides (PhGs) isolated from Calceolaria and Orobanche on platelet aggregation and blood pressure have been investigated. The PhGs tested were able to interfere with platelet aggregation, producing pro- or antiaggregant effects. On the other hand, none of the PhGs tested had a significant effect on blood pressure. The results suggest that the effects of PhGs on rabbit platelets may be related to a differential modulation of cAMP-phosphodiesterase.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
